• contains a significant number of cytokines and essential growth factors
• reduces pain when applied to a wound
• increases and enhances the wound healing process
• has antibacterial properties
• is non-immunogenic (will not be seen as foreign material)
• provides a biological barrier
• provides a matrix for migration and proliferation of cells
• reduces inflammation
• reduces scar tissue formation

1. Faster healing time – Speedy healing times are essential to prevent chronic wound recurrence and minimize the risk of infection. Amniotic membrane is rich in human growth factors and cytokines which initiate the healing response. It also provides a flexible matrix to allow for the migration and rapid growth of cells, making it the ideal medium to facilitate accelerated epithelialization and reduce wound healing times. Research suggests that amniotic membranes have an effect on keratinocytes which allows wounds that were previously unable to epithelialize to heal with healthy granular activity. The healing progressed significantly quicker with amniotic membrane involved than when standard wound care treatments were used. (7)
2. Reduced scarring – Wound fibrosis results in permanent scar tissue forming to replace the normal, parenchymal tissue, thereby altering the structure and function of tissues and organs. Preventing fibrosis is not only aesthetically important but also vital for preserving the barrier function of the skin. (7)
3. Reduced risk of infection – An amniotic membrane allograft provides a protective biological barrier to the wound that prevents infection during healing while simultaneously creating an anti-bacterial layer on the wound. Studies have shown that mesenchymal stromal cells found in amniotic membranes inhibit the formation of fibrosis by reducing the production and retention of B cells which, in turn, modulates the activity of T cells to effectively minimize inflammation. (7)
4. Pain relief – Amniotic membranes have powerful pain-relieving properties. Many researchers believe this is because amniotic membranes reduce inflammation, improve wound bed hydration, and form a protective barrier around exposed nerve endings. Studies have also shown that patients who had undergone a Caesarian section and had amniotic membranes applied to the wound required fewer analgesics than the control group. (7)

The first step is to verify that your insurance company will cover the treatment. To do that, we just need a copy of your insurance card and a photo ID. We will call them to verify that they will cover the procedure. Once you are approved, we will contact you and schedule an exam by the medical staff in our clinic. You will be scheduled to receive the treatment soon thereafter.

You will receive a first treatment with Amniotic Membrane. We do these treatments on either Tuesdays or Fridays. The medical staff will provide post treatment instructions as well. There will be mandatory follow-up visits. This is when the medical staff will perform another examination, review how your wound is responding to the treatment and determine if you should receive additional applications, based on medical necessity.

Wharton’s jelly is administered via a syringe directly to the injured site or defect. The application is relatively painless and takes only a few minutes.

The determination of this is made by your physician, depending on your specific case. However, typically, multiple applications are required to achieve the desired clinical outcome.

There have been no reported graft vs. host interactions or drug interactions with our product. As always, your physician will determine if this product is safe for you. To date, no adverse events contributable to Regenative Labs’ products have been reported in over 50,000 applications.

This is at the discretion of your physician; however, it is generally advisable to take it easy for the first 24-48 hours. Beyond that period, there is typically minimal change in daily activities post-application. Wharton’s jelly application takes only minutes and is non-allogeneic, nonsurgical, and minimally invasive. Patients walk in and walk back out the same day.

Wharton’s jelly allografts are connective tissue supplements crafted to substitute missing or damaged tissue in the patient. If imaging reveals the absence or damage of tissue, you may qualify for Wharton’s jelly application.

If you experience joint pain, there could be an underlying structural tissue defect as the root cause. Rather than addressing only the symptoms (pain) with steroids or other conventional methods, Wharton’s jelly focuses on resolving the root cause by addressing the underlying tissue issue.